Medication & Pharmacology

Dear all, I'm a new member here. In my department an internal assestment is having place, in order to introduce iNO therapy. Beyond economic and clinical aspects, we are now focusing on risk management. In case of device break down during the treatment, the sudden interruption of NO delivery can lead to important injuries for our little patients, in particular if just one device is present within the hospital (I know that several gas companies don't provide an emergency back-up system). Did someone of you encounter the same trouble? How did you solve it? Many thanks, JP

hi all, is there any role of giving antifugals iv prophylactically in lbws or vlbws ? if yes which one is preferred?

Use of anesthetic agents in neonates and young children. Mellon RD, Simone AF, Rappaport BA. Anesth Analg. 2007 Mar;104(3):509-20. Review. LINK TO DOWNLOAD

I found a good recent review of antibiotic use in NICU. The Link is: http://www.jchemother.it/cgi-bin/digisuite.exe/product?ID=1555&IDCategory=128 It is freely available...just click "Read the full text in Adobe FlashPaper (SWF)" to read the full article...You can print it out for your personal use and reference I hope you all will find it useful

Hello Forum, I would be grateful for your thoughts and experiences on a recent acute episode of hemolysis that was neither incompatibillity nor sepsis, and was eventually attributed to the fact that the infant had been receiving a third generation cephalosporin. Ali

Hello, we used caffeine for treatment of neonatal apneas several years ago but recently caffeine is not available in Lithuania. Using theophylline we see more adverse effects and less effectiveness. Could anybody share information about caffeine preparations(Cafcit etc). What company is a distributor or manufacturer of caffeine in EU - both intravenous and oral forms? I know that in some hospitals caffeine is prepared in hospital pharmacies.Thank you. Rasa

Hello: I have a question for the experts. Recently a pharmacist used ranitidine syrup instead of IV preparation as base for dilution for neonatal po med. The package insert states good for infants up to one month, but we have a practice of not using any med preparations with alcohol in our NICU. what is the standard of care in NICUs?

Does anyone use doxapram for apnea of prematurity in addition to caffeine when the apneas are troublesome? If you do use it have you seen any side effects? Jaideep

We recently had an incident where two of the nurses taking care of a baby on nitric oxide fainted, and one doctor complained of lightheadedness. We had the respiratory therapiest check for any leak but he found the connections are ok and that there is no leak. I wonder if anybody had the same incident and what they did to overcome it. Thanks

Pyridoxin dependent seizures, pyridoxal phosphate dep. seizures and folinic acid responsive seizures are all rare conditions. In our clinic we are now updating our knowledge regarding treatment of these conditions. Do you use Pyridoxin or pyridoxal phosphate in neonatal seizures of unknown cause (no infection, asphyxia etc.)? "... there is no biochemical or chemical reason to believe that pyridoxal phosphate will not be as effective as pyridoxine in the treatment of PDE" and " If pyridoxal phosphate is not easily available, pyridoxine should be given as first line therapy. It must, however, not be forgotten that unsuccessful treatment with pyridoxine does no…