99nicu Poll: What is your pharmaceutical management option for PPHN of a term newborn in your institution?

[selvanr4]

PPHN could be idiopathic or secondary and leads to increased pulmonary vascular resistance.There is no clear consensus on the management of PPHN. The goals of treatment are to improve oxygenation, reduce pulmonary vasoconstriction, maintain systemic Blood pressure and perfusion and pulmonary vasodilator therapy.

How do you manage a term newborn baby with PPHN in your institution?

Please note that multiple options/replies can be ticked.

[rehman_naveed]

We also use Sildenifil and Bonsten in severe cases

[Francesco Cardona]

We use Sildenafil as well in selected patients. I would be curious to know if you make a difference if the child is premature or not.

[siddalex]

We use inhaled nitric oxide, along with high O2 sats (92-98%), liberal use of sedation. We use sidenifil more in our cor pulmonale kids

[Urban Rosenqvist]

In most cases, keeping saturation above 93% in combination with good care and keeping the baby warm will suffice. In some cases we use Sildenafil and in the most severe case we refer for NO.

[vito62]

Inhaled nitric oxide, sildenafil, sometimes adenosine

[Moamer]

NO, SILDENAFIL, SEDATION for primary PPHN.

[manuel perez valdez]

we use sildenafil

[Guest perezchawell]

we use sildenafil and keeping warm, sats 92-98%, sedation, nalbufine VAFO

[drchetanshende]

yeah like many others here we also use sildenafil 1mg/kg/dose TDS . convenient , available, cheap.

Plz throw some light on Use of "Bosentin" in Neonatal PPHN by means of any meta-analyses, RCTs. No cochrane review available though on bosentin till date.