Gastrointestinal Issues

Dear all Colleagues "I am currently undertaking a research project examining the microbiota of infants born to mothers with placenta accreta. I would appreciate any additional information or insights that colleagues may have on this topic." Warm Regard Kartika Darma Handayani, MD (Neonatologist) Pediatric Department of Dr.Soetomo General Hospital Airlangga University (UNAIR) Jl. Prof.Dr. Moestopo No. 6-8 Surabaya 60286 I Indonesia (+62) Email : kartika09rama@gmail.com Mobile phone : +62 81359333653

Dear colleagues, I'm a neonatologist in South Brazil and we're writing a new feeding protocol... we frequently disagree about the amount of milk we should start for late preterm/term infants, who cannot breastfeed right away, but can be enterally fed. They are babies that are not so sick that need to be NPO, but still have to be in neonatal ward. Some people calculate same volume as It would be parenterally, some tend to wait to see if baby will be able to breastfeed in the next hours, some tend to start with 10ml... In my opinions and in my readings, it is not very easy to get an agreement... so I would love to read some opinions around the world to chec…

Last week there has been quite som buzz on the social media-site formerly known as Twitter, regarding a decision from the FDA to warn about the use of probiotics in preterm babies. This after a strain of Bifidobacterium Longum was found in a blood culture of a septic preterm infant weighing <1000 g, possibly contributing to the infants death. It was published on September 29th. https://www.fda.gov/media/172606/download?attachment My timeline was filled with people reacting with surprise and also being a bit put down. There has been more and more evidence piling up in favour of probiotic use, and it has been wide spread across many well known centers Two …

hi,a neonate 30days,refer to hospital for icter,bil total 30,direct 20,indirect 10(no kern symptom),your plan!(exchange or no)?if indirect 20 and direct10 ,your plan!(exchange or no)?

We have term baby mother blood group was O positive , antibody negative. Baby was A positive, antibody test positive . Serum bilirubin at 6 hours was 130 mmol/L .started on intensive phototherapy , but serum bilirubin still high was 160 at 10 hours At 24 hours ,serum bilirubin was 220 but direct was 190 mmol/L. Retic count was only 7%. Liver enzymes 3 fold more Gamma GT was 80 then 110 HB was 15 grams .not much changed over first 3 days. US abdomen showed mud in gall bladder. Is this case cholestatic jaundice from start or may be was indirect then becomes direct ?? Inspissated bile syndrome Especially normal colour if stool. …

3 cases of antenatal intestinal perforation so far , we have entertained in our NICU. All term newborns with symptoms like abdominal distension and vomiting on day 2-3 of life, imaging done(X-ray and USG abdomen ) and revealed NEC like picture stage 3 with advance presentation . interestingly, newborn were not so sick clinically. one of them were diagnosed in antenatal period as some pseudocyst around live or pancreas through fetal MRI. Surgical interventions done and all are doing well during follow up. Biopsy of intestinal segment around perforation doesn't reveal any significant pathology.

Which one do you use in follow-up of the newborn? Fenton o Intergrowth ?

14 days old born at 27 week with birth weight 840 gms was on enteral feeds. Suddenly noted to have abdominal diatension platelets 32000 but no ither iasues. Any suggestions about xray.

As you probably know, I also work for Neobiomics - a startup company centered around a dedicated group of clinicians/academics. We would like to learn more about current use / non-use of probiotics and would love to get your feedback. If you complete the survey (takes ~2 min), we will donate 100 SEK (~10€) to Médecins Sans Frontières (MSF), UNICEF or European Foundation for the Care of Newborn Infants (EFCNI) Please note that the survey is only open for respondees based in Europe. https://forms.gle/tbS3f7RbDigT3jEL7

Check out this blog post by Keith Barrington whether transfusions trigger NEC. Or does anemia. https://neonatalresearch.org/2019/04/16/do-transfusions-trigger-nec-or-does-anemia/ I would say that there are enough clinical research data out there to say that there seems to be NO association. Just check out the PINT trial, the RCT comparing a liberal vs a restrictive Hb level for transfusion in preterm infants. If anything, the more liberally transfused group of infant had less NEC. And read this paper by Patel et al that nicely demonstrates that there seems to be confounding of indication coming into play, i.e. it is not the transfusion but the underlying anemia is t…